High pressure homogenizer.
The homogenizers Laboratory Homogenizer 2.
High pressure homogenizer The homogenizers Laboratory Homogenizer 2. Genizer high pressure homogenizers deliver efficient nanoemulsion production, cell disruption, and liposome preparation. ) It works by applying extremely high pressures, typically in the range of 1000-3000 bar (14,500-43,500 psi Aug 3, 2016 · Consequently, some non-thermal pasteurization process have been proposed during the last decades, including high hydrostatic pressure, pulsed electric field, ultrasound (US), and high pressure homogenization (HPH). Our STANSTED High-Pressure Homogenisers provide exceptional performance, versatility, and repeatable results for multiple applications, cell types and materials. Sep 11, 2024 · One common question we are asked, “Why should I use a Microfluidizer instead of a Homogenizer?” Let’s look at each to give you a better idea. These new 55 to 90-kW systems can process up to 13,000 liters per hour at 200 bar. The French Press G-M® continues that tradition. It is an electrically-driven and bench-top, high pressure homogenizer requiring no compressed air or hydraulic oil to achieve maximum 3,062 bar (45,000 psi) operating pressure. The high pressure homogenizer is also called high-pressure fluid nano-homogenizer, which can make the material in the suspension state flow through the cavity (high pressure homogenizer Cavity)with a special internal structure at a high speed under the action of ultra-high pressure (up to 60,000 psi), so that the material undergoes a series of changes in physical, chemical, structural Ultra-high pressure homogenizer is a reciprocating plunger, the material enters the valve group with adjustable pressure under the action of the plunger, and the material loses pressure instantaneously after passing through a specific width limiting gap (working area) It sprays at a very high flow rate (1000-1500 m/s) and collides with the impact ring of one of the collision valve components Genizer specializes in high pressure homogenizers and nano-processing solutions for pharmaceutical, biotech, cosmetic, and food industries. The high-pressure homogenizer (HPH) is one of the earliest and most widely used industrial homogenizers. Feb 1, 2024 · High pressure homogenization (HPH) was first introduced in the early 20th century by Auguste Gaulin (Gaulin, 1904) for processing milk using pressures up to 30 MPa to improve product stability. Dec 17, 2024 · A typical high-pressure homogeniser consists of a high-pressure pump, a homogenising valve, and some additional components, Dec 1, 2024 · High Pressure Homogenization (HPH) is emerging as a cutting-edge, non-thermal technology for liquid food preservation, offering significant advantages over conventional methods. This process causes intense turbulence and shear forces, resulting in particle size Mar 28, 2025 · The most commonly reported high-pressure valve geometries are nozzle, conical piston, needle and seat, microfluidics, sharp angle, and ball and seat [13, 19]. Since positive displacement reciprocating pumps are designed to work with viscous fluids and retain efficiency in the face of variations in flow and pressure, the high-pressure pump is of this type. ABOUT PSI INSTRUMENTS PSI Instruments® is a leader in the design and production of cutting-edge high-pressure homogenizers. High pressure homogenizers can accomplish this task. Jan 6, 2008 · The classic Gaulin or Rannie homogenizer, consisting of a high-pressure pump and homogenizing valve assembly, disperses particles through turbulence and possibly impact generated in the homogenizing valve. Liposome Extruder Accessory: This accessory transforms any Avestin high-pressure homogenizer, such as the C3, D20, C55 and production unit into a liposome extruder. In HPH, liquid is passed through a narrow gap under high pressure where the different processing parameters lead to changes in globule/particle size. A wide variety of homogenizers have been developed to run at different pressures and capacities depending on the product mixture. - Manufacturer of precision medical-grade high-pressure homogenizers and liposome extruders for pharmaceutical and biotech industries Operating the NanoGenizer homogenizer involves the handling of the samples at ultra high pressure. The valve Jul 13, 2020 · (Ultra) high-pressure homogenization ((U)HPH) is one of the emerging technologies being studied and developed for various applications in the food industry. Large selection of standard options as well as special options. We manufacture and supply many types of high-pressure homogenizers. AI generated definition based on: Comprehensive Sampling and Sample Preparation (Second Edition), 2025 The high-pressure homogenizer is a technological marvel in industrial processing, revolutionizing the way various substances are treated and transformed. The use of corrosion-resistant and wear-resistant material is a major concern for complying with Nov 28, 2016 · Learn when you should use low pressure homogenization versus high pressure homogenization. Nov 26, 2016 · Conventional high-pressure homogenization (HPH) is widely used in the pharmaceutical, chemical, and food industries among others. Nov 12, 2024 · High-shear mixing can accommodate a larger starting particle size, though high-pressure homogenization can achieve smaller ending particle sizes. We offer a range of high shear fluid processors, from bench-top laboratory models capable of processing small, investigatory samples, to pilot and production-scale machines capable of handling progressively larger batch sizes. With pressures up to 40,000 psi, you'll be able to achieve highly efficient lysis of even the most resilient cells High-Pressure Pump: A pump generates the necessary pressure to force milk through the homogenization valve. Mar 24, 2025 · Discover how a High-Pressure Homogenizer from IDEX India ensures uniform particle size, improved texture, and enhanced product stability. It uses several technologies—such as high-pressure systems, rotor-stator mechanisms, ultrasonic cavitation, or bead milling—to apply strong shear forces breaking down big particles into Find various types and models of high-pressure homogenizers for creating emulsions and cell lysis. They are suitable for every industry, including the most demanding pharmaceutical, biochemical and food processing environments. Hommak High Pressure Homogenizer for dairy, food beverage, chemical petrochemical, Pharmaceutical, Biotechnology and cosmetics to improve the uniformity and stability of the product; Increase shelf life and reducing particle sizes. Homogenizers. There are several homogenization methods with the mortar and pestle being one of the oldest ways to homogenize materials. Leader in high pressure homogenization High pressure homogenization uses pressure to reduce particles or droplets in emulsions to the required size (usually sub micron). Homogenizer ensures that the fluids passing through it are made homogeneous by reducing their particle sizes with cavitation, shear force, impact velocity, and turbulence effect under pressure. Feb 15, 2021 · In 2019, HST successfully launched its most powerful high-pressure homogenizer, the 355-kW HL8, which can handle 55,000 liters per hour at a homogenizing pressure of 200 bar. It is commonly employed in industries such as food, pharmaceuticals, cosmetics, biotechnology, and chemicals. PSI instruments are leading edge homogenizers, from laboratory to industrial scale, that mix technology and ergonomics. Our ShearJet® processors, parts & services ensure scalable, repeatable results. Reliable, efficient, 3-plunger design for superior particle size reduction & emulsion stability. Have questions? Learn more about high-pressure homogenization in the Application Center or drop us a line. In general, its aim is to produce micron or sub-micron scale emulsions with excellent product characteristics. Understanding these processing parameters with a view to its pharmaceutical Designed for continuous operations, laboratory homogenizers are ideal for high pressure treatment of nano-particles, nano-dispersions, nano-emulsions and for cell disruption; they provide high performance up to a maximum pressure of 2000 bar which means that they are easily usable for different types of applications; biotechnology, pharmaceutical, cosmetics, chemical, dairy, food and beverage High-pressure homogenizers and microfluidizers are often compared because they are both commonly used in the processing of emulsions, suspensions, and dispersions to reduce particle size and achieve a more uniform distribution of particles. Some may use shear, some may use impingement and some You Will Receive: - x1 Sanitary High Pressure Gauge 35,000 psi Sanitary High Pressure Gauge for High Pressure Homogenizer of 35,000 psi as well as other pressure measurements . They are also used in other biotech processes such as the production of nanoparticles for tissue engineering and in the development of new drugs, vaccines, antibiotics, and chemicals. And now, the HLI series has been added to complement the proven HL range. This method is common in milk processing. The pump forces the product under pressure through a small adjustable gap between the valve seat and the valve, causing turbulence and intense Our Best Solutions High-pressure homogenizers and pumps across diverse industries At FBF Italia, we design and build homogenizers and volumetric pumps suitable for a range of sectors, from the food and cosmetic to the chemical and pharmaceutical industries. These high-pressure homogenizers are widely used in food products such as milk, yogurt, ice cream, juices, ketchup, sauces, mayonnaise, creams, and preparations are made with the help of Mar 8, 2024 · High-pressure pumps and homogenization valves make up piston homogenizers, sometimes referred to as high-pressure homogenizers. Jun 24, 2021 · The high-pressure homogenizer instrument encompasses two main components responsible for homogenization and size reduction: (a) high-pressure pump and (b) homogenizing valve. It's capable of producing uniform particle size distrubution and smaller particle sizes. Oct 21, 2022 · Homogenizer A mechanical device known as a homogenizer achieves homogenization. Industrial and laboratory high pressure homogenizers are positive displacement pumps equipped with the compression block and the homogenizing valve able to process a wide range of applications and to enhance the High Shear Homogenizers Our models differ only in their batch size or flow rates, pressure ranges and motor types. Compare features, prices and specifications of electric, pneumatic and hydraulic homogenizers. AI generated definition based on: Ultrasonics Sonochemistry, 2019 Four (4) 100,000 thousandths of an inch What is a High Pressure Homogenizer? A homogenizer consists of a positive displacement pump and a homogenizing valve assembly designed for a specific application. Some applications begin processing samples using high-shear mixing or sonication before ending with high-pressure homogenization. (U)HPH was suggested as an effective tool for achieving microbial safety and extending the product shelf life of liquid foods in a continuous process while minimizing some negative attributes of thermal processing. High Pressure Homogenizers are often the solution particularly useful in the pharmaceutical and biotech industries. The homogenizer A high-pressure homogenizer is a pump with a homogenization device. Common names for the mechanical homogenizing apparatus include Homogenizer, Cell Lysor, High Shear Mixer, Polytron, Rotor Stator Homogenizer BEE homogenizers combine shear, cavitation and impact with greater maximum intensity for more homogeneous emulsions and blends Our lab scale high-pressure homogenizers provide enhanced capabilities for cell rupture, liposomes emulsions, and dispersions in a laboratory setting. This last technique has been demonstrated to have a great potential to provide “fresh-like” products with prolonged shelf-life. It has a high pressure piston pump and a homogenizing valve that can be adjusted to fit customer-specific tasks. It is important to use the right kind of homogenizer pressure! Genizer provides microfluidics mixers, high pressure homogenizers, liposome extruders, nano particle analyzers and nano formulation services for pharmaceutical, biochemical, cosmetics and food industries. View our unique range of systems below. This homogenizer delivers reproducible results for emulsions, dispersions, and cell disruption, helping accelerate product improvement and formulation development with full-scale applicability. PSI-40 is perfect for pilot and medium-sized production batches, even in continuous process configurations. How to Use a High Pressure Homogenizer? 1. Additionally, several limitations and boundaries impede the usage of high-pressure homogenization for Learn about cannabis homogenizers, their types, uses, and how to choose the right one for consistent potency, stability, and product quality. Recent advances in HPH technology, particularly with the development of robust valves capable of withstanding pressures of 350–400 MPa, have opened new possibilities for the food industry. However, its energy consumption is still very high. Installation Place the high-pressure homogenizer on a flat and sturdy desktop, and install the high-pressure pump, homogenizer valve, pressure gauge, check valve, sample tank, and other components one by one after they are in place (each component is relatively independent and can be disassembled and installed independently). Homogenizers High speed tank mixers, Inline High Speed Mixers, Colloid Mixers, and High Pressure Homogenizers are all capable of homogenization. The resulting combination of shear, turbulence, and cavitation reduces particle size and produces uniform mixtures. High pressure homogenization is defined as a process that utilizes a high pressure pump to pass materials through a narrow gap, generating strong breaking forces such as shearing and cavitation, which transform coarse emulsions into nanoemulsions. Therefore, the operation instructions must be well noted to avoid any personal injury by ignoring the instructions or equipment damage by improper operations. As a professional High-Pressure Homogenizer manufacturer and factory in China, LDTD has been in the Homogenizer industry for over 8 years. The equipment used for pharmaceutical and food industries is usually fabricated using stainless steel of high-quality grade. . Feb 24, 2025 · What is Homogenizer? By lowering the size of scattered particles, a homogenizer—which is meant to mechanically mix or disperse heterogeneous mixtures into a homogeneous and stable emulsion—is able. 1 µm Proven construction and long service life Very low noise level Sample volumes from 10 ml processible Deliverable in several sizes and versions for flow capacities from 2 to 100 l/h Robust drive, can also be used for industrial production Optionally available Homogenizers are critical devices in laboratories for breaking down and blending materials into uniform mixtures. The primary purpose of a homogenizer is to reduce particles or globules to High-pressure homogenizers are used in bio-pharmacy applications to obtain intracellular components like enzymes and proteins from bacteria, fungi, and animal cells through cell rupture. The product enters the pump block and is pressurised by the piston pump. Pressures typically range from 1000 to 2500 pounds per square inch (psi), although specific pressures can vary depending on the desired outcome and the type of milk being processed. Renowned for its efficiency, power, and versatility, the HPH has become a top choice in various industrial, pharmaceutical, and food manufacturing processes worldwide, where achieving superior dispersion, particle size reduction, and emulsification is critical for product quality and High-pressure homogenizers In high-pressure homogenization, a product is forced through a narrow orifice at pressures often exceeding 15,000 psi. 20 and Laboratory Homogenizer 2. In this article, we’ll delve into the complexities of high pressure homogenizers, investigating their working PSI instruments are leading edge homogenizers, from laboratory to industrial scale, that mix technology and ergonomics. Overview High pressure homogenizers, such as NanoGenizer, prepare nanomaterial by producing high flow velocity through a small orifice, using a specially designed The Micro DeBEE high-pressure homogenizing system combines the homogenizing forces of most other homogenizers into a single instrument: Before passing through the nozzle, a turbulent flow may be created to vigorously premix the product (like stirrers and agitators). It is also known as a cell lysor, dispenser, high shear mixer, rotor stator homogenizer, or sonicator. The valve geometry 5-plunger homogenizer, equipped with an application-specific homogenizing valve assembly and hydraulic actuation. High pressure homogenizers For many applications in the food, pharmaceutical, cosmetic, biotechnology, and environmental industries, it is necessary to reach particle sizes in a nano range. These instruments use mechanical, ultrasonic, or high-pressure forces to homogenize a wide range of samples, from biological tissues to food products and pharmaceuticals. HPH not only extends the UltraGenier is a laboratory high pressure processing equipment up to 60,000psi. NanoGenizer high pressure homogenizer is composed of a feed reservoir, high pressure pump, transducer, PLC control panel and microfluidics diamond interaction chamber. No moving parts. The equipment needed by the homogenizer includes all the components able to micronize the particles of the fluid and to obtain a homogenous and stable emulsion of the product. For over half a century the French pressure cell press, or "French Press," has been the gold standard for cell lysis. Our homogenizer is up to 150Mpa, we use Nanometer technology in making homogenizer, we are Chinese large homogenizer supplier, our homogenizer also applied in petroleum chemical and bio-engineering industry. Jan 1, 2020 · This type of new homogenization is known as high-pressure homogenization (HPH), and it can be operated at pressure levels of up to 300 MPa, roughly 10- times more than traditional homogenization. 2000 bar. Sonic Mixing's High Pressure Homogenizers create fine emulsions and dispersions with droplet sizes below 1 micron. Each industrial homogenizer is designed to meet the specific needs of applications requiring maximum precision, ensuring consistent and high-quality results. Donghua is high pressure homogenizer manufacturer in China since 1984, offer wear-resistant high pressure industrial and laboratory homogenizer for customer demands, homogenizer is for homogenization in food, fine chemicals, pharmaceutical and biological engineering industry. Dec 11, 2019 · Background The high pressure homogenizer (HPH) in pharmaceutical industry is specifically used for size reduction, mixing, and stabilization of dispersions or droplets. It operates by applying high pressure to materials, forcing them through a narrow gap, breaking down particles to a fine size, enhancing product consistency and quality. This adaptable piece of machinery is essential in industries ranging from food and pharmaceuticals to cosmetics and biotechnology. High pressure homogenizers, prepare nanomaterial by producing high flow velocity through a small orifice, using a specially designed internal fixed geometry under The working principle of the high-pressure homogenizer (HPH) is based on the use of a high-pressure pump and a valve (nozzle, orifice), which makes the equipment large, heavy, and expensive. Homogenizer is an efficient industrial or laboratory equipment that breaks solid and liquid particles into uniform and consistent mixtures. The pressure of a conventional homogenizer is within 15,000 psi, while a high pressure homogenizer can achieve 30,000 psi, and an ultra-high pressure homogenizer can reach up to 60,000 psi. Featuring high pressure and precision-engineered valves, our homogenizers create turbulence and shear that break down particles and distribute components evenly to enhance product characteristics. Both technologies use high pressure to achieve this, but they differ in their mechanisms of action and the specific applications for which they are best Industrial Mixing Equipment: high pressure homogenizers, inline blending systems, liquid process equipment, colloid mills & propeller mixers. An in-depth understanding of fluid dynamics The PL300 ShearJet® benchtop processor is a pneumatic drive high pressure processor capable of being your everyday R & D tool and a small batch processor. Rannie 57T and Gaulin 57T Series – High Pressure Homogenizers The more modular and flexible design of the APV 57T makes it suitable for a wide range of applications in dairy, food, beverage, industrial and pharmaceutical industries. Genizer specializes in high pressure homogenizers and nano-processing solutions for pharmaceutical, biotech, cosmetic, and food industries. Labs and large hygienic plants have no room for hundreds of Dec 1, 2022 · Despite being a technology of several decades, high pressure homogenization (HPH) remains widely used in food and pharmaceutical industries, often as an essential unit operation in liquid product Feb 1, 2024 · High pressure homogenization (HPH) was first introduced in the early 20th century by Auguste Gaulin (Gaulin, 1904) for processing milk using pressures up to 30 MPa to improve product stability. Despite being a technology of several decades, high pressure homogenization (HPH) remains widely used in food and pharmaceutical industries, often as an essential unit operation in liquid product processing Continual advanc. Genizer technology can be applied to nanomedicine, such as nanoparticles, nanoemulsions, liposomes, vaccines, gene delivery systems, as well as cell disruption, graphene and nanotube Abstract (Ultra) high pressure homogenization ( (U)HPH) processing, also called dynamic high pressure processing, provides opportunity to promote sustainable food processing and meet the current challenge to ensure the availability of sufficient, safe, nutritious, tasty, and convenient food to the rapidly expanding and more affluent population. High-Pressure Homogenizers High-pressure homogenizers work by forcing a sample at high pressure through a narrow valve or aperture. By utilizing high pressure and intense Abstract (Ultra) high-pressure homogenization ((U)HPH) is one of the emerging technologies being studied and developed for various applications in the food industry. The PL300 has proven to be capable of exceeding all competitors for process efficiency due to the Reaction Chamber® set energy transfer rates and superior product temperature control. 50 are laboratory homogenizers with an easy installation (no need of water for cooling of pistons) and use (manual adjustment of homogenizing pressure via hand wheels). High-performance APV Rannie® 132T and Gaulin® 132T homogenizers for Dairy, Food, Pharma & more. Explore our advanced technologies including microfluidic systems, diamond chambers, and liposome extruders. It utilizes the high-pressure homogenizer's power to shear the lipid solution through a track-etched polycarbonate membrane to produce liposomes. This reduction creates a stable dispersion in the finished product, and provides a starting point for further production processes. It was invented in the early 1900s by Auguste Gaulin for homogenizing milk. High-pressure homogenization (HPH) has been employed for unit operations like com-minution, mixing, and stabilization of phar-maceutical solids and nanoparticles. With advancing nanotechnology, the HPH tech-nique has undergone discernible evolution and has broadened the scope of its pharma-ceutical applications by facilitating particle engineering. Homogenizers & High-Pressure Pumps Industries like pharmaceutical and dairy use the process of homogenization on materials like liquid drugs, pills, and milk products to ensure uniformity throughout the solution. At the same time, prepare Jul 22, 2024 · What is a high pressure homogenizerWhat is a high-pressure homogenizer? A high-pressure homogenizer (HPH) is equipment used to emulsify, mix two or more liquids together that are not normally immiscible, such as oil and water, or to reduce the size of particles in a liquid (micronization. GEA Industrial homogenizers are machines made by two essential elements: a compression block, which allows to pump the product in high pressure and a homogenizing valve, able to micronize dispersed particles down to the order of micrometers and nanometers, depending on product’s characteristics and the desired results. Our cutting-edge technology guarantees a flawless homogenization process, delivering superior-quality finished products. During the homogenization process, changes in physical, chemical, structural properties occur, and as a result, homogeneous suspension takes place at nanoscale. High Pressure Homogenizers are used for homogenization of compounds that require high pressure for the processes. The French Press G-M is the highest pressure hydraulic press that is commercially available for laboratory use. This equipment is designed to reduce particle size to the nanometer range, making it ideal for applications that require fine and uniform mixing. The PL300 capabilities make it desirable because of Donghua is high pressure homogenizer manufacturer in China since 1984, offer colloid mill, industrial and laboratory homogenizer for food, beverage, chemical and pharmaceutical industry. Advantages of the IKA high pressure homogenizer HPH: Highest possible energy input which allows for a particle reduction of up to 0. Avestin Inc. Benefits of Using a Homogenizer Industry-leading high pressure homogenizers for nano particle size reduction. Designed for continuous operation at high pressure, our benchtop homogenizers offer a compact design, simple installation, convenience, ease of use, and easy maintenance. High-pressure homogenization is defined as a technique used to break down and homogenize substances by applying high pressures to force the sample through a small gap, creating intense shear forces and turbulence that disrupt cell membranes, reduce particle sizes, and promote mixing. Designed for laboratory, pilot, and industrial-scale applications with precise pressure control and repeatability. In today’s environment, homogenizers are used to produce more consistent emulsions in a high efficiency process. The HPH is an inline dispersing machine that produces superfine emulsions by spontaneous decompression of the liquid from max. Process volumes from Lab research scale to production systems with leading pressure capability and temperature control. For example, IKA high pressure homogenizer HPH is used for the homogenizing of dairy products, disintegration of cellulose in vegetables, production of ATS industrial high-pressure homogenizers offer outstanding versatility and a wide range of capacities (up to 4000 l/h & The high pressure homogenizer is an advanced piece of equipment designed to improve the uniformity and stability of various emulsions, suspensions, and cell disruptions. net makes finding the best homogenizer for your lab easy! We have a great selection, expert knowledge, and tools to help you make the right choice. Its products are characterized by their innovative solutions, their high-quality manufacturing, and their extreme durability. Common Types of Homogenizers There are several common types of homogenizers and each homogenizer uses a different set of principles and mechanisms to achieve homogenization. Find your high-pressure homogenizer easily amongst the 16 products from the leading brands (SILVERSON, NETZSCH, OMVE, ) on DirectIndustry, the industry specialist for your professional purchases. Introduction High pressure homogenization (HPH) was first introduced in the early 20th century by Gaulin (Gaulin, 1904) for improve product stability. A homogenizer is generally needed when a high-efficiency break-up of the fat globules is required. High-pressure homogenizers are most commonly used for creating emulsions and for cell lysis when relatively large volumes are being processed. es in the technology are made on multiple fronts, on equipment innovations by the manufacturers, new applications by users, and advances in process understanding by A high pressure homogenizer is a machine used for precise and efficient homogenization processes. The choice of a high Mar 11, 2023 · High Pressure Homogenizer 1. The basic operational principle of HPH remains unchanged since and it involves using a high-pressure pump to force the fluid through a small orifice. 3) For safety, do not point the inlet or outlet of high pressure devices and equipment supplied by Genizer, including high pressure homogenizer, extruder, interaction chamber and valve, to any personnel or object that may affect safety or induce property loss. Stansted Fluid Power Products Ltd (SFPP) specialises in High Pressure Engineering systems for liquids and gases, at low medium and high pressure pressures all the way up to 1400 MPa (200,000 psi, 14000 bar). The homogenization process improves product uniformity by mixing immiscible liquids into a stable emulsion. Auguste Gaulin developed homogenizers to blend milk. It is an electrically-driven and bench-top high shear homogenizer. 1. NanoGenizer is a laboratory high pressure processing device. A positive displacement, three-piston pump with capillary tubes installed at the discharge made up the apparatus. Advancements in high-pressure homogenizer valves have led to the development of microfluidization, also known as dynamic high-pressure microfluidization. fszmcyclejlaiimjrijslwqnnwtesxjtktwkazhnbwxneucgznjzvruulrvwkholfvdyejkblwwtenvzyt